David N. Bolam

The paper annotates CAZymes in five parasitic trichomonads, identifying 1,406 genes and revealing conserved mucin O-glycan-targeting and antibacterial CAZyme toolkits.

This study identifies a novel carbohydrate-binding module (CBM) family in a human gut microbiota beta-mannanase, revealing its unusual molecular architecture and functional specificity for beta-mannan.

This study identifies PNGaseL from Flavobacterium akiainvivens as an enzyme with broad N-glycan specificity, outperforming PNGaseF and PNGaseA in cleaving diverse glycan structures.

The paper shows arylsulfamates inhibit Bacteroides growth on sulfated glycans via a lipid kinase, not carbohydrate sulfatases, and identifies resistance mechanisms.

This study identifies a mucin-induced PUL in Bacteroides thetaiotaomicron that processes mucin-O-glycoproteins and metabolizes N-acetylgalactosamine, highlighting its role in microbiota-gut homeostasis.

This study characterizes carbohydrate-active enzymes from Akkermansia muciniphila to show they synergistically degrade mucin O-glycans to the core GalNAc.

The paper identifies and characterizes anhydro-sialic acid transporters in bacteria, showing their specific or promiscuous substrate preferences.