Increased excitation-inhibition balance due to a loss of GABAergic synapses in the serine racemase knockout model of NMDA receptor hypofunction
Shekib A. Jami, Scott Cameron, Jonathan M. Wong, Emily R. Daly, A. Kimberley McAllister, John A. Gray
The paper investigates the relationship between NMDA receptor hypofunction and GABAergic synapse loss in SRKO mice, finding reduced inhibitory synapses and increased excitation-inhibition imbalance.
Journal of Neurophysiology · May 26, 2021Peer-reviewedNeuroscience