The VGCC auxiliary subunit α2δ1 is an extracellular GluA1 interactor and regulates LTP, spatial memory, and seizure susceptibility
Gerardo Leana-Sandoval, Ananth V. Kolli, Matthew A. Sandoval, Emily Saavedra, Kathy H. Li, Lulu Y. Chen, Alma L. Burlingame, Jorge Ramírez‐Franco, Javier Díaz-Alonso
This study identifies α2δ1 as an extracellular GluA1 interactor that regulates LTP, spatial memory, and seizure susceptibility through its role in AMPAR trafficking.
bioRxiv · Dec 2, 2024 · PreprintNeuroscience