Cell Numbers Contribute to Cell Fate During Ciona Cardiopharyngeal Mesoderm Specification
Emily Singer, Haram Kim, Michael Levine, Nicholas Treen
The paper shows that cell number control via Cdkn1.b in Ciona embryos affects cell fate, leading to heart development failure when cell division is arrested early.
Proceedings of the National Academy of Sciences · Jan 8, 2026Peer-reviewedDevelopmental Biology