Forward genetic screen in zebrafish identifies new fungal regulators that limit host-protective Candida-innate immune interaction
Bailey A. Blair, Emma Bragdon, Gursimran K. Dhillon, Nnamdi Baker, Lena Ann Stasiak, Mya Muthig, Pedro Miramón, Michael C. Lorenz, Robert T. Wheeler
The paper identifies new fungal regulators in zebrafish that modulate Candida-phagocyte interactions, with NMD5 playing a key role in limiting phagocytosis and virulence.
mBio · Apr 4, 2025Peer-reviewedMicrobiology