A temporal map of maternal immune activation-induced changes reveals a shift in neurodevelopmental timing and perturbed cortical development in mice.
César P. Canales, Myka L. Estes, Karol Cichewicz, Kartik Angara, John Paul Aboubechara, Scott Cameron, Kathryn Prendergast, Linda Su-Feher, Iva Zdilar, Ellie J. Kreun, Emma C Connolly, Jin Myeong Seo, Jack B. Goon, Kathleen Farrelly, Tyler W. Stradleigh, , Alex S. Nord
This study identifies transcriptomic and neuroanatomical changes in mouse embryos exposed to maternal immune activation, revealing altered neurodevelopmental timing and cortical development.
bioRxiv · Jun 13, 2020 · PreprintNeuroscience