Homeostatic neuroimmune rhythms are linked to priming of olfactory bulb responses to an intranasal inflammatory challenge
Gregory Pearson, Brennan A. Baca, Jiexin Wang, Patrícia Reis, Stephanie Gottwals, Nathan Santos, Emma C. Burke, Giancarlo Denaroso, Amy Burnside, Saïd Akli, Ilia N. Karatsoreos
The paper shows that time of day influences the olfactory bulb's response to inflammatory challenges through rhythmic immune gene expression and microglial activity in mice.
Cell Reports · Mar 20, 2026Peer-reviewedImmunology