Ilia N. Karatsoreos

ThermoClock is an automated temperature control system that models circadian entrainment and disruption in 2D and 3D in vitro models, showing that ramp time and cycle duration affect rhythm strength and wound healing.

The paper shows that time of day influences the olfactory bulb's response to inflammatory challenges through rhythmic immune gene expression and microglial activity in mice.

This study shows that endocannabinoid signaling via CB1r mediates metabolic dysfunction caused by circadian desynchronization, with the liver playing a key role.

This study shows that perinatal circadian desynchronization disrupts sleep and prefrontal cortex function in male mice but not females.

This study uses a novel ex vivo model to investigate acute and chronic neural responses to mild traumatic brain injury in the hippocampus, linking injury forces to cellular and functional changes.

The paper shows circadian rhythms in glutamate release and synaptic throughput in the NTS, with light-phase release and dark-phase action potential firing.

This study shows circadian desynchronization reduces information throughput in prefrontal cortex neurons in mice, independent of daily rhythms, through GIRK channel sensitivity changes.

This study examines lactate metabolism in the medial prefrontal cortex of aged and circadian desynchronized mice, finding disruptions in circadian rhythms and gene expression related to neurometabolism.

This study shows BMAL1 regulates astrocyte activation and function through cell-autonomous and non-cell-autonomous mechanisms, impacting neuronal survival and brain health.