AKAP5 and Caveolin-1 organize opposing nanodomains that regulate smooth muscle contraction and blood pressure
Yen‐Lin Chen, Maniselvan Kuppusamy, Fênix Araujo, Yashu Tang, Zdravka Daneva, Kyosuke Kazama, Lojy M. Hozyen, Emma D Chung, Saainikedhana Venugopal, Sree S. Katragadda, Grace C. Garcia, Divine C. Nwafor, Stephen B.G. Abbott, Richard D. Minshall, Ryan T Kellogg, Swapnil K. Sonkusare
The paper identifies AKAP5 and caveolin-1 as organizers of opposing nanodomains that regulate smooth muscle contraction and blood pressure through distinct signaling pathways.
bioRxiv · Aug 21, 2026 · PreprintPhysiology