Divine C. Nwafor

The paper identifies AKAP5 and caveolin-1 as organizers of opposing nanodomains that regulate smooth muscle contraction and blood pressure through distinct signaling pathways.

This study shows that TNAP activity in brain endothelial cells maintains barrier integrity via the ROCK pathway, and its inhibition leads to barrier dysfunction.

This study shows that experimental stroke in male mice leads to chronic gut dysbiosis and neuroinflammation lasting up to one month.

This study shows that reduced TNAP enzyme activity in cerebral microvessels during late sepsis is linked to neuroinflammation and behavioral changes like anti-nociception.