Author

Yen‐Lin Chen

University of VirginiaORCID 0000-0003-1149-394XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Swapnil K. SonkusareiD· 2 shared Avril V. SomlyoiD· 1 shared Chris ChristieiD· 1 shared Divine C. NwaforiD· 1 shared Emma D Chung· 1 shared Eric M. SmalliD· 1 shared Fênix AraujoiD· 1 shared Grace C. Garcia· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

Swapnil K. SonkusareORCID

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintAug 21, 2026

AKAP5 and Caveolin-1 organize opposing nanodomains that regulate smooth muscle contraction and blood pressure

Yen‐Lin Chen, Maniselvan Kuppusamy, Fênix Araujo…·Swapnil K. Sonkusare

The paper identifies AKAP5 and caveolin-1 as organizers of opposing nanodomains that regulate smooth muscle contraction and blood pressure through distinct signaling pathways.

DOI 10.64898/2026.08.13.744495

humanexperimental assay

𝕏 PostBluesky

PhysiologybioRxivPreprintMar 12, 2025

Deletion of RSK2 kinase alleviates age-dependent hypertension

Ramon Jose Ayon, Yves T. Wang, Jaspreet Kalra…·Avril V. Somlyo

This study shows that deleting RSK2 kinase in aged mice reduces hypertension by improving vascular relaxation and reducing vessel stiffness.

DOI 10.1101/2025.03.12.642932

mouseexperimental assay

𝕏 PostBluesky