Nuclear DNA Damage Response Triggers Reorganization of Mitochondrial Nucleic Acids
Chenxiao Yu, Emma Evens, Sidney Tchiong, Marite Castromonte Albinagorta, Joshua Okletey, Marco Tigano
This study identifies mito-blobs as nuclear DNA damage-induced mitochondrial structures that concentrate immunogenic nucleic acids and influence inflammatory gene expression through autophagic clearance.
bioRxiv · May 25, 2026 · PreprintCell Biology