The Role of BAZ2-dependent Chromatin Remodeling in Suppressing G4 DNA Structures and Associated Genomic Instability
Adrianna L. Vandeuren, Kierney O’Dare, Rosemary H. C. Wilson, Patrick van Eijk, Lindsay R. Julio, Shannon G. MacLeod, Ella Chee, Annika Salpukas, Emma M. Kriz, George A. Lantz, Shellaina J.V. Gordon, Simon J. Elsässer, Simon Huw Reed, Tovah A. Day
This study identifies BAZ2 chromatin remodelers as suppressors of G4 DNA structures and shows that their depletion increases G4 formation and genomic instability.
bioRxiv · Dec 10, 2024 · PreprintMolecular Biology