Twist-Dependent Elastic Limits and Unwinding of Tightly Bent DNA
Soumya Chandrasekhar, Emma Meyer, Fatemeh Fadaei, Rachel Bricker, Thomas Swope, Morgan Schreck, Mark Macri, Draven Houser, Daniel Hollis, John J. Portman, Thorsten L. Schmidt
This study investigates the elastic limits of tightly bent DNA under torsional strain, finding that DNA can be bent to 3.0 nm without kinking when helical repeats are 11 bp/turn due to twist-bend coupling.
bioRxiv · Feb 14, 2024 · PreprintBiophysics