A coordinated and reproducible multicellular response to AD pathology
Gabriele Vilkaite, Emma Volcov, Lijun An, Yu Xiao, Inès Hristovska, Camila Rosat Consiglio, Alexa Pichet Binette, Niklas Mattsson, Chris Gaiteri, Jacob W. Vogel
The paper identifies robust multicellular axes associated with Alzheimer's disease pathology and sex using single-cell data from 427 donors, validated in an independent dataset.
bioRxiv · Oct 23, 2026 · PreprintNeuroscience