Spatial organization of enzymes and cofactors in synthetic membrane-associated condensates (sMACs)
Ka‐Hei Siu, Virginia Jiang, Eoin M Gaffney, Mackenzie T. Walls, Jerelle A. Joseph, José L. Avalos
The paper demonstrates that synthetic membrane-associated condensates (sMACs) can be engineered to enhance metabolic functions by creating localized redox microenvironments through cofactor partitioning.
bioRxiv · Apr 27, 2026 · PreprintSynthetic Biology