Virginia Jiang

Structural insights into xyloglucan recognition by an ABC transporter from a Gram-positive, thermophilic bacterium

The paper identifies an ABC transporter for xyloglucan uptake in Anaerocellum bescii and solves its substrate-binding protein structure, revealing a unique mode of xyloglucan recognition.

Enhanced GPP synthesis by Erg20p-peptide fusions and biomolecular condensates boosts monoterpene production in yeast

The paper enhances monoterpene production in yeast by using Erg20p-peptide fusions and biomolecular condensates to increase GPP synthesis over FPP synthesis.

Spatial organization of enzymes and cofactors in synthetic membrane-associated condensates (sMACs)

The paper demonstrates that synthetic membrane-associated condensates (sMACs) can be engineered to enhance metabolic functions by creating localized redox microenvironments through cofactor partitioning.

A Highly Conserved ABC Transporter Mediates Cello-Oligosaccharide Uptake in the Extremely Thermophilic, Lignocellulolytic Bacterium Anaerocellum (f. Caldicellulosiruptor) bescii

This study identifies an ABC transporter in Anaerocellum bescii responsible for cello-oligosaccharide uptake, showing genetic deletion impairs growth on cellulose and cellobiose.

An RNA-mediated DNA melting mechanism for CRISPR-Cas9

This study identifies an RNA-mediated DNA melting mechanism in CRISPR-Cas9 using simulations and experiments, showing RNA bases intercalate to promote strand separation.

Maltodextrin Transport in the Extremely Thermophilic, Lignocellulose Degrading Bacterium Anaerocellum bescii (f. Caldicellulosiruptor bescii)

This paper identifies and characterizes two maltodextrin ABC transporters in Anaerocellum bescii, revealing their substrate specificity and biophysical properties to enhance understanding of oligosaccharide transport in thermophilic bacteria.

Computational Structure Prediction Provides a Plausible Mechanism for Electron Transfer by the Outer Membrane Protein Cyc2 from Acidithiobacillus ferrooxidans

The paper presents a computational model of the Cyc2 protein from Acidithiobacillus ferrooxidans, proposing a mechanism for ferrous iron electron transfer.