IL-18 produced by pregnant uterus promotes essential inflammatory responses and fetoplacental growth
Hajime Ino, Yasuyuki Negishi, Yumi Horii, Eri Koike, Richard Anthony Flavell, Shunji Suzuki, Rimpei Morita
This study identifies IL-18 as a critical factor produced by pregnant uterine smooth muscle cells that supports placental development and fetoplacental growth, with implications for maternal and fetal health.
Cell Reports · Jan 1, 2026Peer-reviewedImmunology