Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma
Gonzalo López, Karina L. Conkrite, Miriam Doepner, Komal S. Rathi, Apexa Modi, Zalman Vaksman, Lance M. Farra, Eric Hyson, Moataz Noureddine, Jun Stephen Wei, Malcolm Anders Smith, Shahab Asgharzadeh, Robert C. Seeger, Javed Iqbal Khan, Jaime M. Guidry Auvil, , Sharon J. Diskin
This study identifies somatic structural variations in neuroblastoma, showing their enrichment in neurodevelopmental genes and the tumor suppressor role of SHANK2.
Genome Research · Sep 1, 2020Peer-reviewedGenomics