Author

Daniela Se Gerhard

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Research Focus:variant calling· 3 Assay:whole-genome sequencing· 3 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Gonzalo LópeziD· 2 shared Jaime M. Guidry AuviliD· 2 shared Javed Iqbal KhaniD· 2 shared John M. MarisiD· 2 shared Jun Stephen WeiiD· 2 shared Karina L. ConkriteiD· 2 shared Lance M. Farra· 2 shared Sharon J. DiskiniD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Gonzalo LópezORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The landscape of structural variation in pediatric cancer

Robert Greenhalgh, Samuel W. Brady, Wentao Yang, Diane A. Flasch, Michael N. Edmonson, Nadezhda V. Terekhanova, Yanling Liu, Jian Wang, Karol A. Szlachta, Liqing Tian, Daniel K. Putnam, Delaram Rahbarinia, Pandurang S. Kolekar, Xin Zhou, Daniela Se Gerhard, , Jinghui Zhang

This study analyzes structural variants in 1,616 pediatric cancer genomes, revealing unique SV hotspots and patterns distinct from adult cancers.

Cancer Cell · Mar 12, 2026Peer-reviewedCancer Biology

Germline pathogenic variants in 786 neuroblastoma patients

Jung Kim, Zalman Vaksman, Laura E. Egolf, Rebecca Kaufman, Perry Evans, Karina L. Conkrite, Arnavaz Danesh, Gonzalo López, Michael P. Randall, Maiah H. Dent, Lance M. Farra, Neil Menghani, Malwina Dymek, Heena Desai, Ryan M. Hausler, , Sharon J. Diskin

This study identifies 13.9% of neuroblastoma patients with pathogenic germline variants in cancer predisposition genes, associated with worse survival and enriched in DNA repair genes like BARD1.

medRxiv · Jan 23, 2023 · PreprintGenetic & Genomic Medicine

Framework For Quality Assessment Of Whole Genome, Cancer Sequences

Justin P. Whalley, Ivo Buchhalter, Esther Rheinbay, Keiran M. Raine, Kortine Kleinheinz, Miranda D. Stobbe, Johannes Werner, Sergi Beltrán, Marta Gut, Daniel Hübschmann, Barbara Hutter, Dimitri G. Livitz, Marc D. Perry, Mara W. Rosenberg, Gordon Saksena, , Ivo Glynne Gut

The paper introduces a framework for assessing the quality of whole genome cancer sequences using a star rating system based on five QC measures, providing a tool for researchers to evaluate and exclude low-quality data.

Nature Communications · Oct 7, 2020Peer-reviewedGenomics

Somatic structural variation targets neurodevelopmental genes and identifies SHANK2 as a tumor suppressor in neuroblastoma

Gonzalo López, Karina L. Conkrite, Miriam Doepner, Komal S. Rathi, Apexa Modi, Zalman Vaksman, Lance M. Farra, Eric Hyson, Moataz Noureddine, Jun Stephen Wei, Malcolm Anders Smith, Shahab Asgharzadeh, Robert C. Seeger, Javed Iqbal Khan, Jaime M. Guidry Auvil, , Sharon J. Diskin

This study identifies somatic structural variations in neuroblastoma, showing their enrichment in neurodevelopmental genes and the tumor suppressor role of SHANK2.

Genome Research · Sep 1, 2020Peer-reviewedGenomics