Humanization of the rpb9 locus in fission yeast reveals conserved and divergent roles of rpb9 and human POLR2I
Jared M. Finkel, Micah G. Williams, Mamta B Nirmal, Samakshi Pandey, Erik D. Howe, C. Liu, Jeremy R. Lohman, Nimisha Sharma, Tommy V. Vo
This study humanizes the rpb9 gene in fission yeast to examine the functional and structural conservation of POLR2I, revealing both conserved and divergent roles in growth, aging, stress responses, and chemoresistance.
Genes · May 27, 2026Peer-reviewedSynthetic Biology