Directed evolution for cell separation in natural isolates of budding yeast reveals selection to deactivate AMN1 and the Rim101 pathway in haploids and selection in favor of Hawthorne's deletion in diploids
Benjamin Galeota-Sprung, Erik Pritchard, Crystal Huang, Amy Fernandez, P. D. Sniegowski
The paper evolves natural yeast isolates to select for cell separation, identifying AMN1 deactivation and Rim101 pathway mutations in haploids, and Hawthorne's deletion in diploids as key adaptations.
G3 Genes Genomes Genetics · Jan 23, 2026Peer-reviewedEvolutionary Biology