Mechanical tension expands the microtubule lattice stepwise and modulates kinesin-1 binding in an isoform-dependent manner
Yannic Lurz, Benedikt S. J. Fischer, Jaya Mishra, Laura Muras, Erik Schäeffer, E. Michael Ostap, Nisha Mohd Rafiq, Igor M. Kulić, Serapion Pyrpassopoulos
This paper measures how mechanical tension affects microtubule lattice expansion and kinesin-1 binding, showing isoform-dependent responses and a critical switching force.
bioRxiv · Jun 22, 2026 · PreprintBiophysics