Nisha Mohd Rafiq

The paper identifies curved microtubule regions as markers of lattice compaction and shows how lattice states regulate protein recruitment and signaling in cells and neurons.

This paper measures how mechanical tension affects microtubule lattice expansion and kinesin-1 binding, showing isoform-dependent responses and a critical switching force.

The paper investigates transcriptomic changes in oligodendroglial lineage cells from PD patient-iPSCs with LRRK2-G2019S mutation, identifying altered pathways and signaling in OPCs and ODCs.

This study identifies synaptogyrin family proteins as key regulators of dopamine vesicle formation, overriding canonical synaptic vesicle size constraints and contributing to dopaminergic terminal vulnerability in Parkinson's disease.

The paper uses proximity labeling to compare interaction partners of TOMM20 and TOMM70, finding RBPs preferentially associate with TOMM20 and their association increases under translation stress.

The paper characterizes synaptic vesicles in iPSC-derived dopaminergic neurons, revealing distinct secretory vesicle pools with different molecular and ultrastructural features.

This study investigates how a mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons, revealing impaired protein clearance and altered Ca2+ channel distribution.