Author

Serapion Pyrpassopoulos

University of TübingenORCID 0000-0002-9728-9239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Jaya MishraiD· 2 shared Nisha Mohd RafiqiD· 2 shared Barbara BirkiD· 1 shared Benedikt S. J. FischeriD· 1 shared E. Michael OstapiD· 1 shared Erik Schäeffer· 1 shared Igor M. KulićiD· 1 shared Ke Wang· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

Jaya MishraORCID

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2 papers

Recent·Most cited

Curved microtubule regions mark sites of lattice compaction in cells and neurons

Jaya Mishra, Polina Volos, Ke Wang, Barbara Birk, Laura Trefftz, Serapion Pyrpassopoulos, Nisha Mohd Rafiq

The paper identifies curved microtubule regions as markers of lattice compaction and shows how lattice states regulate protein recruitment and signaling in cells and neurons.

bioRxiv · Aug 5, 2026 · PreprintCell Biology

Mechanical tension expands the microtubule lattice stepwise and modulates kinesin-1 binding in an isoform-dependent manner

Yannic Lurz, Benedikt S. J. Fischer, Jaya Mishra, Laura Muras, Erik Schäeffer, E. Michael Ostap, Nisha Mohd Rafiq, Igor M. Kulić, Serapion Pyrpassopoulos

This paper measures how mechanical tension affects microtubule lattice expansion and kinesin-1 binding, showing isoform-dependent responses and a critical switching force.

bioRxiv · Jun 22, 2026 · PreprintBiophysics