Biochemical analysis of the endoribonuclease activity of the human mitochondrial topoisomerase 1
Cyrielle P. J. Bader, Erika Kasho, Josefin M. E. Forslund, Aiswarya Dash, Malgorzata Wessels, Paulina H. Wanrooij
This study investigates the endoribonuclease activity of hTop1mt and finds it less efficient than hTop1, explaining the tolerance of rNMPs in mtDNA.
Nucleic Acids Research · Jun 6, 2025Peer-reviewedBiochemistry