The type III-B CRISPR-Cas System Affects Energy Metabolism and Adaptation in the Archaeon Saccharolobus solfataricus
Erika Wimmer, Logan H. Hodgskiss, Melina Kerou, Isabelle Anna Zink, Christa Schleper
This study shows that deleting the type III-B CRISPR-Cas system in Saccharolobus solfataricus increases growth rate but reduces adaptability to carbon source changes, with upregulated genes related to energy metabolism and transport.
bioRxiv · Sep 2, 2024 · PreprintMicrobiology