Deep single-cell immune and signaling profiles predict long term therapy response in chronic myeloid leukemia within hours
Stein‐Erik Gullaksen, Mathias Brevik, Øystein Sefland, Erin Craig, Monica Hellesøy, Ulla Olsson‐Strömberg, Jesper Stentoft, Johan Richter, Tobias Gedde‐Dahl, Robert John Tibshirani, Sylvia K. Plevritis, Dominik Georg Friedrich Wolf, Satu M. Mustjoki, Henrik Hjorth‐Hansen, Bjørn Tore Gjertsen
The paper uses mass cytometry to analyze immune and signaling profiles in CML patients within hours of TKI treatment to predict 12-month treatment response.
bioRxiv · Nov 10, 2025 · PreprintCancer Biology