Temporal Dynamics of Nucleus Accumbens Neurons in Male Mice During Reward Seeking
Terra A. Schall, King-Lun Li, Xiguang Qi, Brian T. Lee, William J. Wright, Erin E. Alpaugh, Rachel J. Zhao, Jianwei Liu, Qize Li, Bo Zeng, Lirong Wang, Yanhua H. Huang, Oliver M. Schlüter, Eric J. Nestler, Edward H. Nieh, Yan Dong
The paper identifies three temporally sequenced clusters of NAc neuron activity in mice during reward seeking and shows that D1 and D2 neuron activity at specific times predicts and influences lever-pressing behavior.
Nature Communications · Oct 28, 2024Peer-reviewedNeuroscience