Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion
Elena V. Aleksandrova, Kelvin J. Y. Wu, Ben I. C. Tresco, Egor A. Syroegin, Erin E. Killeavy, Samson M. Balasanyants, Maxim S. Svetlov, Steven T. Gregory, Gemma Catherine Atkinson, Andrew G. Myers, Yury S. Polikanov
This study determines the structural basis of Cfr-mediated antimicrobial resistance and identifies mechanisms for evading it through ribosome structures with Cfr-modified 23S rRNA.
bioRxiv · Sep 27, 2023 · PreprintMolecular Biology