Elena V. Aleksandrova

Structural insights into context-specific inhibition of bacterial translation by macrolides

This study presents structural analysis of ribosome-nascent chain complexes to elucidate how macrolides inhibit bacterial translation in a context-specific manner.

Structural basis of Cfr-mediated antimicrobial resistance and mechanisms for its evasion

This study determines the structural basis of Cfr-mediated antimicrobial resistance and identifies mechanisms for evading it through ribosome structures with Cfr-modified 23S rRNA.

Insights into the ribosome function from the structures of non-arrested ribosome nascent chain complexes.

The paper reports structures of non-arrested ribosome nascent chain complexes, revealing new insights into ribosome function and the mechanism of the peptidyl transferase center.