NaV1.7-dependent peripheral sensitization drives chronic pain in Parkinson's disease
Tyler S. Nelson, Naomi K Grabus, Heather N. Allen, Aida Calderón‐Rivera, Santiago Loya‐López, Erick Josué Rodríguez-Palma, Alaina L. Waters, Eslam Elhanafy, Stephanie I. Shiers, Ishwarya Sankaranarayanan, Kimberly Gómez, Theodore John Price, Rajesh Khanna
This study identifies NaV1.7-dependent peripheral sensitization as a mechanism of chronic pain in Parkinson's disease and highlights CRMP2 regulation of NaV1.7 as a therapeutic target.
bioRxiv · Sep 15, 2026 · PreprintNeuroscience