Combined lactate and hypothermia therapy enhances neuroprotection following neonatal hypoxic-ischemic brain injury
Ifrah Omar Ibrahim, Sébastien Giraud, Estelle Lemarie, Marie-Christine Beauvieux, Stéphane Sanchez, Marc Biran, Aurélien Trottier, Karine Viaud, Jean‐François Chateil, Jean Delmas, Luc Pellerin, Hélène Roumes, Anne‐Karine Bouzier‐Sore
This study shows that combining lactate with hypothermia improves neuroprotection in neonatal hypoxic-ischemic brain injury by enhancing lesion recovery and reducing neuroinflammation and apoptosis.
bioRxiv · Oct 1, 2026 · PreprintNeuroscience