Author
Erasmus MC
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Marieke E. van Leeuwen, Beatrice F. Tan, Evelyne Wassenaar…·Joost H. Gribnau
The paper introduces DCM-time machine (DCM-TM) to track gene and enhancer activity during human iPSC differentiation, showing its ability to label active elements and correlate methylation changes with cell state transitions.
Lieke Koornneef, Sari E. van Rossum-Fikkert, Esther Sleddens–Linkels…·Alex N. Zelensky
This paper investigates the role of BRCA2's meiotic domain in meiotic homologous recombination and proposes a model of chromosome pairing through tensed DNA tethers.
Ruben Boers, Joachim Boers, Beatrice F. Tan…·Joost H. Gribnau
The paper uses a novel method to track enhancer activity and transcriptome changes during intestinal stem cell differentiation, revealing insights into lineage decisions and chromatin dynamics.
Lieke Koornneef, Johan A. Slotman, Esther Sleddens–Linkels…·Willy M. Baarends
This study uses multi-color dSTORM microscopy to analyze RAD51 and DMC1 organization at meiotic DSBs in Hormad1-/- mice, revealing altered recombinase configurations and synaptonemal complex structure.
Rania Ghouil, Simona M. Miron, Lieke Koornneef…·Alex N. Zelensky
This paper identifies a cryptic BRCA2 repeated motif that binds to HSF2BP oligomers but does not affect meiotic recombination.