Developmental BiologybioRxivPreprint
Human DCM-time machine unravels cell state changes during primitive gut tube differentiation
Marieke E. van Leeuwen, Beatrice F. Tan, Evelyne Wassenaar…·Joost H. Gribnau
The paper introduces DCM-time machine (DCM-TM) to track gene and enhancer activity during human iPSC differentiation, showing its ability to label active elements and correlate methylation changes with cell state transitions.
DOI 10.1101/2025.09.26.678757