Phylo-Plex: A phylogenetically informed, low-cost amplicon sequencing platform for deployable high-resolution genomic epidemiology
Mathew A. Beale, Vignesh Shetty, Kirsty Ambridge, George Lacey, Sam Dougan, William Roberts-Sengier, Beth Sampher, Florent Lassalle, Matthew J. Dorman, Mahlape P. Mahlangu, Johanna M. E. Venter, Bianca Da Costa Dias, Martha Chipinduro, Tendai Washaya, Luanne Rodgers, , Nicholas Robert Thomson
Phylo-Plex is a low-cost amplicon sequencing method for high-resolution genomic epidemiology, achieving fine-scale lineage discrimination comparable to whole-genome sequencing in resource-limited settings.
Nature Communications · Jul 9, 2026Peer-reviewedGenetic & Genomic Medicine