Author

Sam Dougan

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetic & Genomic Medicine· 1 Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Alan TraceyiD· 1 shared Alasdair J. NisbetiD· 1 shared Alison A. MorrisoniD· 1 shared Andrew J. BalmeriD· 1 shared Beauty Makamure· 1 shared Benjamin M. RumneyiD· 1 shared Beth SampheriD· 1 shared Bianca Da Costa DiasiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperGenomics

Alan TraceyORCID

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Author profile →

3 papers

Recent·Most cited

Phylo-Plex: A phylogenetically informed, low-cost amplicon sequencing platform for deployable high-resolution genomic epidemiology

Mathew A. Beale, Vignesh Shetty, Kirsty Ambridge, George Lacey, Sam Dougan, William Roberts-Sengier, Beth Sampher, Florent Lassalle, Matthew J. Dorman, Mahlape P. Mahlangu, Johanna M. E. Venter, Bianca Da Costa Dias, Martha Chipinduro, Tendai Washaya, Luanne Rodgers, , Nicholas Robert Thomson

Phylo-Plex is a low-cost amplicon sequencing method for high-resolution genomic epidemiology, achieving fine-scale lineage discrimination comparable to whole-genome sequencing in resource-limited settings.

Nature Communications · Jul 9, 2026Peer-reviewedGenetic & Genomic Medicine

Spatial lung niches shape Pseudomonas aeruginosa persistence

Cecilia Katunge Kyanya, Duy Pham, Nana-Jane Chipampe, Phumrapee Boonklang, Louise Ellison, Andrew J. Balmer, Catherine Tudor, Jasmine Halliwell, Hon Man Chan, Vanessa Bonita Pereira, Benjamin M. Rumney, Holly Anderson, Shevaniee Umamaheswaran, Mia Franulović, Terry K. Judah, , Josephine M. Bryant

This study uses spatial transcriptomics to map Pseudomonas aeruginosa niches in lung tissue from CF and COPD patients, revealing distinct bacterial states and host interactions linked to infection persistence.

bioRxiv · Jul 7, 2026 · PreprintImmunology

Chromosomal genome assembly resolves drug resistance loci in the parasitic nematode Teladorsagia circumcincta

Jennifer McIntyre, Alison A. Morrison, Kirsty Maitland, Duncan Berger, Daniel R. G. Price, Sam Dougan, Dionysios Grigoriadis, Alan Tracey, Nancy E. Holroyd, Katie Bull, Hannah Rose Vineer, Mike J. Glover, Eric Rene Morgan, Alasdair J. Nisbet, Tom N. McNeilly, , Stephen R. Doyle

The paper generates a chromosome-scale genome assembly for Teladorsagia circumcincta and identifies genetic loci associated with drug resistance to improve anthelmintic resistance diagnostics.

PLoS Pathogens · Feb 6, 2025Peer-reviewedGenomics