Microglial brain-derived neurotrophic factor (BDNF) supports the behavioral and synaptogenic effects of ketamine
Samuel C. Woodburn, Alexander M. Kuhn, Kelly E Bosis, David T. Dadosky, Etienne J. Mueller, Justin L. Bollinger, Rosa Maria Salazar Gonzalez, J. Elliott Robinson, Lauren Larke Vollmer, Eric S. Wohleb
This study shows that microglial BDNF is essential for ketamine's antidepressant and synaptogenic effects in the prefrontal cortex.
Brain Behavior and Immunity · Jul 2, 2026Peer-reviewedNeuroscience