Author

Evan N. Smith

University of North Carolina at Chapel HillPrimary ORCID profile (0009-0008-1927-047X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Evan N. SmithiD1 paper · Massachusetts General Hospital

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:differential expression· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Clyde W. HodgeiD· 3 shared Jessica L. HoffmaniD· 3 shared Sara Faccidomo· 3 shared Seth M. Taylor· 3 shared Abigail E. Agoglia· 2 shared Ashley M. May· 2 shared Ciarra M. WhindletoniD· 2 shared April Kim· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Clyde W. HodgeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TARP γ-8 is a target of ethanol that regulates self-administration and relapse in mice

Sara Faccidomo, Jessica L. Hoffman, Julie Lee, Ciarra M. Whindleton, Michelle H. Kim, Seth M. Taylor, April Kim, Caroline Richter, Hanna L. Seiters, James Bryant, Ashley Chang, Evan N. Smith, Abigail E. Agoglia, Susumu Tomita, Melissa A. Herman, Clyde W. Hodge

This study shows that TARP γ-8 regulates ethanol reinforcement and relapse in mice, with reduced self-administration and cue-induced reinstatement in TARP γ-8 heterozygous null mice.

bioRxiv · Mar 27, 2025 · PreprintNeuroscience

Inhibition of AMPA receptors bound to transmembrane AMPA receptor regulatory protein γ-8 (TARP γ-8) blunts the positive reinforcing properties of alcohol and sucrose in a brain region-dependent manner

Jessica L. Hoffman, Sara Faccidomo, Seth M. Taylor, Kristina G. DeMiceli, Ashley M. May, Evan N. Smith, Ciarra M. Whindleton, Clyde W. Hodge

This study inhibits TARP γ-8 bound AMPARs in specific brain regions to show their role in alcohol and sucrose reinforcement, finding region-specific effects on reward behavior.

bioRxiv · Dec 14, 2022 · PreprintNeuroscience

Alcohol Drinking Exacerbates Neural and Behavioral Pathology in the 3xTg-AD Mouse Model of Alzheimer’s Disease

Jessica L. Hoffman, Sara Faccidomo, Michelle Kim, Seth M. Taylor, Abigail E. Agoglia, Ashley M. May, Evan N. Smith, L.C. Wong, Clyde W. Hodge

This study shows that non-dependent alcohol drinking worsens AD-like neural and behavioral issues in 3xTg-AD mice.

International review of neurobiology · Jan 1, 2019Peer-reviewedNeuroscience