Jessica L. Hoffman

This study shows that TARP γ-8 regulates ethanol reinforcement and relapse in mice, with reduced self-administration and cue-induced reinstatement in TARP γ-8 heterozygous null mice.

This study shows that ethanol self-administration increases GluA2-containing AMPAR expression and synaptic activity in the nucleus accumbens, which enhances ethanol's reinforcing effects through an NSF-dependent mechanism.

This study inhibits TARP γ-8 bound AMPARs in specific brain regions to show their role in alcohol and sucrose reinforcement, finding region-specific effects on reward behavior.

This study shows that calcium-permeable AMPA receptors and GluA1 trafficking in the basolateral amygdala regulate alcohol reinforcement in mice.

This study shows that non-dependent alcohol drinking worsens AD-like neural and behavioral issues in 3xTg-AD mice.