Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau
Maxime W.C. Rousseaux, Jean‐Pierre Revelli, Gabriel E. Vázquez-Vélez, Ji‐Yoen Kim, Evelyn Craigen, Kristyn A. Gonzales, Jaclyn Beckinghausen, Huda Yahya Zoghbi
This study shows that reducing Trim28 in adult mice is safe and lowers levels of alpha-synuclein and tau.
eLife · Jun 4, 2018Peer-reviewedNeuroscience