Author

Jean‐Pierre Revelli

Baylor College of MedicineORCID 0000-0002-4789-3104Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Huda Yahya ZoghbiiD· 5 shared Ashley G. AndersoniD· 2 shared Yan LiiD· 2 shared Alexander L. HaniD· 1 shared Bakhos Tadros· 1 shared Bhupesh VaidyaiD· 1 shared Bradley T. HymaniD· 1 shared Cameron OstermaniD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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5 shared papersNeuroscience

Huda Yahya ZoghbiORCID

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Author profile →

5 papers

Recent·Most cited

Druggable CSNK2A1-MeCP2 regulatory axis links Okur-Chung neurodevelopmental syndrome with MECP2-related disorders

Ashley G. Anderson, Srinivas Chamakuri, Rebecca Meyer-Schuman, Elizabeth Hai-Yen Chu, Jean-Pierre Revelli, Jiyoen Kim, Manar Zaghlula, Surabi Veeraragavan, Damian W Young, Huda Y Zoghbi

The paper identifies a druggable CSNK2A1-MeCP2 regulatory axis linking Okur-Chung neurodevelopmental syndrome with MECP2-related disorders through CRISPR screens and mouse models.

bioRxiv · Nov 6, 2026 · PreprintNeuroscience

GLP-1 analogs restore inflammatory, mitochondrial and intercellular signaling networks in the SncaG51D/G51D knock-in mouse model of Parkinson's disease

Bhupesh Vaidya, Yan Li, Young Doo Kim, Cameron Osterman, Jean‐Pierre Revelli, Huda Yahya Zoghbi

GLP-1 analogs improve motor and non-motor deficits and reduce gliosis and insoluble α-synuclein in a Parkinson's disease mouse model.

bioRxiv · May 19, 2026 · PreprintNeuroscience

Early transcriptional signatures of MeCP2 positive and negative cells in Rett syndrome

Yan Li, Ashley G. Anderson, Guangtong Qi, Sih‐Rong Wu, Jean‐Pierre Revelli, Zhandong Liu, Huda Yahya Zoghbi

The paper identifies early transcriptional differences between MeCP2 positive and negative cells in Rett syndrome models, revealing sex-specific molecular effects in excitatory and inhibitory circuits.

bioRxiv · Jun 26, 2025 · PreprintNeuroscience

The big tau splice isoform resists Alzheimer's-related pathological changes

Dah‐eun Chloe Chung, Xue Deng, Hari Krishna Yalamanchili, Jean‐Pierre Revelli, Alexander L. Han, Bakhos Tadros, Ronald Richman, Michelle Dias, Fatemeh Alavi Naini, Steven Boeynaems, Bradley T. Hyman, Huda Yahya Zoghbi

This study identifies big tau, a splice isoform of tau, as more abundant in brain regions resistant to Alzheimer's pathology and shows its protective properties in human patients.

bioRxiv · Jul 30, 2024 · PreprintNeuroscience

Depleting Trim28 in adult mice is well tolerated and reduces levels of α-synuclein and tau

Maxime W.C. Rousseaux, Jean‐Pierre Revelli, Gabriel E. Vázquez-Vélez, Ji‐Yoen Kim, Evelyn Craigen, Kristyn A. Gonzales, Jaclyn Beckinghausen, Huda Yahya Zoghbi

This study shows that reducing Trim28 in adult mice is safe and lowers levels of alpha-synuclein and tau.

eLife · Jun 4, 2018Peer-reviewedNeuroscience