Molecular BiologyScientific ReportsPeer-reviewed
Altered polyadenylation site usage in SERPINA1 3'UTR in response to cellular stress affects A1AT protein expression
F N U Jiamutai, Abigail Hatfield, Austin Herbert…·Lela Lackey
The paper shows that IL-6 induces altered polyadenylation in SERPINA1, increasing long 3UTR isoforms that repress A1AT protein expression during inflammation.
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