Sodium channel toxin-resistance mutations do not govern batrachotoxin (BTX) autoresistance in poison birds and frogs
F. Abederemane-Ali, N. D. Rossen, M. E. Kobiela, R. A. Craig, C. E. Garrison, L. A. O'Connell, J. Du Bois, J. P. Dumbacher, D. L. Minor
The paper shows that Nav mutations are not responsible for BTX resistance in poison frogs and birds, suggesting alternative mechanisms like toxin sequestration.
bioRxiv · Oct 29, 2020Biophysics