Author

F. Acosta-Reyes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 3 Research Focus:benchmarking· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Approach:simulation· 1 Organism:virus· 1

Frequent Co-Authors

J. Frank· 3 shared E. Seitz· 2 shared A. Ourmazd· 1 shared A. T. Bogetti· 1 shared F. L. Kearns· 1 shared G. Mashayekhi· 1 shared I. Fernandez· 1 shared J. A. Goldsmith· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

J. Frank

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A glycan gate controls opening of the SARS-CoV-2 spike protein

T. E. Sztain, S.-H. Ahn, A. T. Bogetti, L. Casalino, J. A. Goldsmith, E. Seitz, R. S. McCool, F. L. Kearns, F. Acosta-Reyes, S. Maji, G. Mashayekhi, J. A. McCammon, A. Ourmazd, J. Frank, J. S. McLellan, , R. E. Amaro

This study identifies a glycan gate and key residues that facilitate SARS-CoV-2 spike protein RBD opening through simulations and experimental validation.

bioRxiv · Feb 15, 2021Biophysics

Simulation of cryo-EM ensembles from atomic models of molecules exhibiting continuous conformations

E. Seitz, F. Acosta-Reyes, P. Schwander, J. Frank

This paper simulates cryo-EM ensembles from atomic models of molecules with continuous conformations to test machine learning methods for free energy landscape reconstruction.

bioRxiv · Dec 3, 2019 · PreprintBiophysics

The Israeli Acute Paralysis Virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.

I. Fernandez, J. Frank, F. Acosta-Reyes, R. Neupane

The paper characterizes the IAPV IRES structure using cryo-EM to show how it captures host ribosomes and redirects them to viral mRNA, providing insights for RNA-interference strategies against CCD.

bioRxiv · Apr 11, 2019Biophysics