Spindle scaling is governed by cell boundary regulation of microtubule nucleation
E. Rieckhoff, F. Berndt, S. Golfier, F. Decker, M. Elsner, K. Ishihara, J. Brugues
The paper shows that microtubule nucleation, not polymerization, governs spindle scaling across all cell sizes by regulating nucleation inhibitor partitioning to the cell membrane.
Current Biology · Dec 1, 2020Peer-reviewedCell Biology