Joint degeneration in a mouse model of pseudoachondroplasia: ER stress, inflammation and autophagy blockage
J. T. Hecht, A. C. Veerisetty, M. G. Hossain, D. Patra, F. Chiu, F. Coustry, K. L. Posey
This study identifies ER stress, inflammation, and autophagy blockage as key mechanisms in joint degeneration in a mouse model of pseudoachondroplasia, suggesting potential therapeutic targets.
bioRxiv · Jun 4, 2021Pathology