D. Patra

BRCA1 Hypermethylation In Sporadic Breast Cancers: Discovering A Novel Pathway To Tumorigenesis Via Coordinate NBR2 Deregulation And TNBC Transformation

This study identifies a novel pathway in sporadic breast cancers where BRCA1 hypermethylation leads to NBR2 deregulation, TNBC transformation, and aggressive tumor behavior through altered transcript ratios and hormone receptor dynamics.

Joint degeneration in a mouse model of pseudoachondroplasia: ER stress, inflammation and autophagy blockage

This study identifies ER stress, inflammation, and autophagy blockage as key mechanisms in joint degeneration in a mouse model of pseudoachondroplasia, suggesting potential therapeutic targets.

SARS-CoV-2 viral budding and entry can be modeled using virus-like particles

This study develops a BSL-2-compatible system using SARS-CoV-2 virus-like particles to model viral budding and entry mechanisms and assess drug inhibitors.

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

This study identifies CLK1 as a novel drug target in Trypanosoma brucei by showing its essential role in kinetochore function and cell survival through kinase inhibition.