Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells
E. Bergsten, D. Mestivier, F. Donnadieu, T. Pedron, C. Barau, L. Tsoumtsa, A. Mettouchi, E. Lemichez, O. Gorgette, M. Chamaillard, A. Vaysse, S. Volant, A. Doukani, P. J. Sansonetti, I. Sobhani, G. Nigro
This study shows that Parvimonas micra phylotype A alters DNA methylation and gene expression in intestinal epithelial cells, potentially contributing to colorectal cancer.
bioRxiv · May 14, 2022 · PreprintMicrobiology