Author

I. Sobhani

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Mettouchi· 2 shared A. Vaysse· 2 shared D. Mestivier· 2 shared E. Bergsten· 2 shared E. Lemichez· 2 shared M. Chamaillard· 2 shared T. Pedron· 2 shared A. Doukani· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

A. Mettouchi

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The Colibactin-Producing Escherichia coli alters the tumor microenvironment to immunosuppressive lipid overload facilitating colorectal cancer progression and chemoresistance.

N. de Oliveira Alves, G. Dalmasso, D. Nikitina, A. Vaysse, R. Ruez, L. Ledoux, T. Pedron, E. Bergstein, O. Boulard, L. Autier, S. Allam, L. Motreff, P. Sauvanet, D. Letourneur, J. Gagniere, , M. Chamaillard

This study shows that Colibactin-producing Escherichia coli creates an immunosuppressive lipid-rich tumor microenvironment that promotes colorectal cancer progression and chemoresistance.

bioRxiv · Mar 13, 2023 · PreprintCancer Biology

Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells

E. Bergsten, D. Mestivier, F. Donnadieu, T. Pedron, C. Barau, L. Tsoumtsa, A. Mettouchi, E. Lemichez, O. Gorgette, M. Chamaillard, A. Vaysse, S. Volant, A. Doukani, P. J. Sansonetti, I. Sobhani, G. Nigro

This study shows that Parvimonas micra phylotype A alters DNA methylation and gene expression in intestinal epithelial cells, potentially contributing to colorectal cancer.

bioRxiv · May 14, 2022 · PreprintMicrobiology

Extensive Transmission of Microbes along the Gastrointestinal Tract

T. S. Schmidt, M. R. Hayward, L. P. Coelho, S. S. Li, P. I. Costea, A. Y. Voigt, J. Wirbel, O. M. Maistrenko, R. J. Alves, E. Bergsten, C. de Beaufort, I. Sobhani, A. Heintz-Buschart, S. Sunagawa, G. Zeller, , P. Bork

The paper shows oral microbes commonly colonize the large intestine in healthy individuals and more so in disease states like colorectal cancer and rheumatoid arthritis.

bioRxiv · Dec 28, 2018Microbiology